Samantha Who? the TV comedy series starring Emmy winner Christina Applegate, Jean Smart and Barry Watson was created by Cecelia Ahern and Don Todd.
The show is about a 30-year-old psychiatrist who, after becoming the victim of a hit-and-run, develops amnesia and has to rediscover her life, her relationships and herself.
Samantha Who? is scheduled to air on Monday nights on ABC, following Dancing with the Stars.
- Christina Applegate as Samantha “Sam” Newly
- Kevin Dunn as Howard
- Jennifer Esposito as Andrea
- Melissa McCarthy as Dena
- Tim Russ as Frank
- Jean Smart as Regina
- Barry Watson as Todd
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